Abstract
Background: Gossypol has recently been identified as a potential anticancer agent. In this study, a novel liposomal formulation is evaluated for delivery of gossypol. Materials and Methods: Gossypol was incorporated into liposomes. The liposomes were characterized for physical and chemical properties and for in vitro cytotoxicity. Results: Gossypol was stably encapsulated in these liposomes and exhibited cytotoxicity towards cancer cells. Conclusion: Liposomes can be used effectively as gossypol carriers.
| Original language | English |
|---|---|
| Pages (from-to) | 2801-2805 |
| Number of pages | 5 |
| Journal | Anticancer Research |
| Volume | 28 |
| Issue number | 5 A |
| State | Published - Sep 2008 |
| Externally published | Yes |
ASJC Scopus Subject Areas
- Oncology
- Cancer Research
Keywords
- Gossypol
- Liposome
- PEG-DSPE
- TPGS