A multifaceted exercise intervention did not alter cognitive function and cerebral perfusion in individuals with Parkinson's disease

B. S. Pollock; C. A. Peacock; E. J. Ryan; M. B. Spitznagel; A. L. Ridgel

doi:10.1016/j.scispo.2019.05.008

A multifaceted exercise intervention did not alter cognitive function and cerebral perfusion in individuals with Parkinson's disease

B. S. Pollock
, C. A. Peacock
, E. J. Ryan
, M. B. Spitznagel
, A. L. Ridgel

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives: To investigate cerebral perfusion as a potential mechanism of exercise-related cognitive improvements and to further associate cognition and cerebral perfusion in Parkinson's disease. Equipment and methods: Cerebral perfusion was measured continuously at rest and during a cognitive task using near-infrared spectroscopy before and after a multifaceted exercise program in thirteen individuals with Parkinson's disease. Results: Cognitive function was not significantly impaired in our group of Parkinson's disease participants at baseline. Cerebral perfusion (69.91% ± 2.43) was significantly greater during cognitive testing than while resting (68.12% ± 2.42) (P ≤ 0.001). Our results are inconclusive with respect to the effect of exercise on cognitive dysfunction in PD.

Original language	English
Pages (from-to)	101.e1-101.e7
Journal	Science and Sports
Volume	35
Issue number	2
DOIs	https://doi.org/10.1016/j.scispo.2019.05.008
State	Published - Apr 2020

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Masson SAS

ASJC Scopus Subject Areas

Orthopedics and Sports Medicine

Keywords

Cerebrovascular circulation
Cognition
Exercise
Parkinson disease

Access to Document

10.1016/j.scispo.2019.05.008

Cite this

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title = "A multifaceted exercise intervention did not alter cognitive function and cerebral perfusion in individuals with Parkinson's disease",

abstract = "Objectives: To investigate cerebral perfusion as a potential mechanism of exercise-related cognitive improvements and to further associate cognition and cerebral perfusion in Parkinson's disease. Equipment and methods: Cerebral perfusion was measured continuously at rest and during a cognitive task using near-infrared spectroscopy before and after a multifaceted exercise program in thirteen individuals with Parkinson's disease. Results: Cognitive function was not significantly impaired in our group of Parkinson's disease participants at baseline. Cerebral perfusion (69.91\% ± 2.43) was significantly greater during cognitive testing than while resting (68.12\% ± 2.42) (P ≤ 0.001). Our results are inconclusive with respect to the effect of exercise on cognitive dysfunction in PD.",

keywords = "Cerebrovascular circulation, Cognition, Exercise, Parkinson disease",

author = "Pollock, \{B. S.\} and Peacock, \{C. A.\} and Ryan, \{E. J.\} and Spitznagel, \{M. B.\} and Ridgel, \{A. L.\}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Masson SAS",

year = "2020",

month = apr,

doi = "10.1016/j.scispo.2019.05.008",

language = "English",

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journal = "Science and Sports",

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TY - JOUR

T1 - A multifaceted exercise intervention did not alter cognitive function and cerebral perfusion in individuals with Parkinson's disease

AU - Pollock, B. S.

AU - Peacock, C. A.

AU - Ryan, E. J.

AU - Spitznagel, M. B.

AU - Ridgel, A. L.

PY - 2020/4

Y1 - 2020/4

N2 - Objectives: To investigate cerebral perfusion as a potential mechanism of exercise-related cognitive improvements and to further associate cognition and cerebral perfusion in Parkinson's disease. Equipment and methods: Cerebral perfusion was measured continuously at rest and during a cognitive task using near-infrared spectroscopy before and after a multifaceted exercise program in thirteen individuals with Parkinson's disease. Results: Cognitive function was not significantly impaired in our group of Parkinson's disease participants at baseline. Cerebral perfusion (69.91% ± 2.43) was significantly greater during cognitive testing than while resting (68.12% ± 2.42) (P ≤ 0.001). Our results are inconclusive with respect to the effect of exercise on cognitive dysfunction in PD.

AB - Objectives: To investigate cerebral perfusion as a potential mechanism of exercise-related cognitive improvements and to further associate cognition and cerebral perfusion in Parkinson's disease. Equipment and methods: Cerebral perfusion was measured continuously at rest and during a cognitive task using near-infrared spectroscopy before and after a multifaceted exercise program in thirteen individuals with Parkinson's disease. Results: Cognitive function was not significantly impaired in our group of Parkinson's disease participants at baseline. Cerebral perfusion (69.91% ± 2.43) was significantly greater during cognitive testing than while resting (68.12% ± 2.42) (P ≤ 0.001). Our results are inconclusive with respect to the effect of exercise on cognitive dysfunction in PD.

KW - Cerebrovascular circulation

KW - Cognition

KW - Exercise

KW - Parkinson disease

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IS - 2

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A multifaceted exercise intervention did not alter cognitive function and cerebral perfusion in individuals with Parkinson's disease

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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