A short procedure for synthesis of 4-ethynyl-2,2,6,6-tetramethyl-3,4-dehydro-piperidine-1-oxyl nitroxide

P. M. Gannett; E. Darian; J. H. Powell; E. M. Johnson

doi:10.1081/SCC-100104464

A short procedure for synthesis of 4-ethynyl-2,2,6,6-tetramethyl-3,4-dehydro-piperidine-1-oxyl nitroxide

P. M. Gannett
, E. Darian
, J. H. Powell
, E. M. Johnson

Research output: Contribution to journal › Article › peer-review

Abstract

The spin-probe labeling technique has been applied to DNA and offers the possibility of studying antisense agents in cells. Simpler syntheses of spin-probes for incorporation into DNA would facilitate this. Here, we describe the synthesis of a new spin probe that requires half the number of steps of related 5 ring nitroxide.

Original language	English
Pages (from-to)	2137-2141
Number of pages	5
Journal	Synthetic Communications
Volume	31
Issue number	14
DOIs	https://doi.org/10.1081/SCC-100104464
State	Published - 2001
Externally published	Yes

ASJC Scopus Subject Areas

Organic Chemistry

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10.1081/SCC-100104464

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abstract = "The spin-probe labeling technique has been applied to DNA and offers the possibility of studying antisense agents in cells. Simpler syntheses of spin-probes for incorporation into DNA would facilitate this. Here, we describe the synthesis of a new spin probe that requires half the number of steps of related 5 ring nitroxide. ",

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AU - Gannett, P. M.

AU - Darian, E.

AU - Powell, J. H.

AU - Johnson, E. M.

PY - 2001

Y1 - 2001

N2 - The spin-probe labeling technique has been applied to DNA and offers the possibility of studying antisense agents in cells. Simpler syntheses of spin-probes for incorporation into DNA would facilitate this. Here, we describe the synthesis of a new spin probe that requires half the number of steps of related 5 ring nitroxide.

AB - The spin-probe labeling technique has been applied to DNA and offers the possibility of studying antisense agents in cells. Simpler syntheses of spin-probes for incorporation into DNA would facilitate this. Here, we describe the synthesis of a new spin probe that requires half the number of steps of related 5 ring nitroxide.

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U2 - 10.1081/SCC-100104464

DO - 10.1081/SCC-100104464

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SN - 0039-7911

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EP - 2141

JO - Synthetic Communications

JF - Synthetic Communications

IS - 14

ER -

A short procedure for synthesis of 4-ethynyl-2,2,6,6-tetramethyl-3,4-dehydro-piperidine-1-oxyl nitroxide

Abstract

ASJC Scopus Subject Areas

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