Anticonvulsants

Meghan M. Vallejo; Karen Berger

doi:10.1007/978-3-031-62224-3_20

Anticonvulsants

Meghan M. Vallejo
, Karen Berger

Department of Pharmacy Practice

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Prompt recognition and treatment of seizures and status epilepticus in the neurointensive care unit is vital. Understanding of the available anticonvulsant treatment options, including mechanism of action, pharmacodynamics, adverse effects, and formulations available, can assist the clinician with selecting and adding agents to a treatment regimen where little evidence is available to guide therapy after the second or third line of therapy. Particular focus is placed on anticonvulsants commonly or potentially used for the treatment of adult patients with status epilepticus. Agents reviewed in this chapter include benzodiazepines, fosphenytoin/phenytoin, valproic acid, levetiracetam, phenobarbital, lacosamide, topiramate, perampanel, clobazam, brivaracetam, and anesthetic agents including midazolam, propofol, pentobarbital, and ketamine.

Original language	English
Title of host publication	Textbook of Neurointensive Care
Subtitle of host publication	Perioperative Management, Monitoring, Pharmacotherapy: Volume 2
Publisher	Springer Nature
Pages	347-365
Number of pages	19
Volume	2
ISBN (Electronic)	9783031622243
ISBN (Print)	9783031622236
DOIs	https://doi.org/10.1007/978-3-031-62224-3_20
State	Published - Jan 1 2024

Bibliographical note

Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2024, corrected publication 2025.

ASJC Scopus Subject Areas

General Medicine
General Neuroscience

Access to Document

10.1007/978-3-031-62224-3_20

Cite this

@inbook{addee444ec2945ac99db81e5815a2df7,

title = "Anticonvulsants",

abstract = "Prompt recognition and treatment of seizures and status epilepticus in the neurointensive care unit is vital. Understanding of the available anticonvulsant treatment options, including mechanism of action, pharmacodynamics, adverse effects, and formulations available, can assist the clinician with selecting and adding agents to a treatment regimen where little evidence is available to guide therapy after the second or third line of therapy. Particular focus is placed on anticonvulsants commonly or potentially used for the treatment of adult patients with status epilepticus. Agents reviewed in this chapter include benzodiazepines, fosphenytoin/phenytoin, valproic acid, levetiracetam, phenobarbital, lacosamide, topiramate, perampanel, clobazam, brivaracetam, and anesthetic agents including midazolam, propofol, pentobarbital, and ketamine.",

author = "Vallejo, \{Meghan M.\} and Karen Berger",

note = "Publisher Copyright: {\textcopyright} The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2024, corrected publication 2025.",

year = "2024",

month = jan,

day = "1",

doi = "10.1007/978-3-031-62224-3\_20",

language = "English",

isbn = "9783031622236",

volume = "2",

pages = "347--365",

booktitle = "Textbook of Neurointensive Care",

publisher = "Springer Nature",

}

TY - CHAP

T1 - Anticonvulsants

AU - Vallejo, Meghan M.

AU - Berger, Karen

N1 - Publisher Copyright: © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2024, corrected publication 2025.

PY - 2024/1/1

Y1 - 2024/1/1

N2 - Prompt recognition and treatment of seizures and status epilepticus in the neurointensive care unit is vital. Understanding of the available anticonvulsant treatment options, including mechanism of action, pharmacodynamics, adverse effects, and formulations available, can assist the clinician with selecting and adding agents to a treatment regimen where little evidence is available to guide therapy after the second or third line of therapy. Particular focus is placed on anticonvulsants commonly or potentially used for the treatment of adult patients with status epilepticus. Agents reviewed in this chapter include benzodiazepines, fosphenytoin/phenytoin, valproic acid, levetiracetam, phenobarbital, lacosamide, topiramate, perampanel, clobazam, brivaracetam, and anesthetic agents including midazolam, propofol, pentobarbital, and ketamine.

AB - Prompt recognition and treatment of seizures and status epilepticus in the neurointensive care unit is vital. Understanding of the available anticonvulsant treatment options, including mechanism of action, pharmacodynamics, adverse effects, and formulations available, can assist the clinician with selecting and adding agents to a treatment regimen where little evidence is available to guide therapy after the second or third line of therapy. Particular focus is placed on anticonvulsants commonly or potentially used for the treatment of adult patients with status epilepticus. Agents reviewed in this chapter include benzodiazepines, fosphenytoin/phenytoin, valproic acid, levetiracetam, phenobarbital, lacosamide, topiramate, perampanel, clobazam, brivaracetam, and anesthetic agents including midazolam, propofol, pentobarbital, and ketamine.

UR - https://www.scopus.com/pages/publications/105007586940

UR - https://www.scopus.com/pages/publications/105007586940#tab=citedBy

U2 - 10.1007/978-3-031-62224-3_20

DO - 10.1007/978-3-031-62224-3_20

M3 - Chapter

AN - SCOPUS:105007586940

SN - 9783031622236

VL - 2

SP - 347

EP - 365

BT - Textbook of Neurointensive Care

PB - Springer Nature

ER -

Anticonvulsants

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this