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Application of the hypoxic model in estimation of cerebral blood flow by electrochemically generated hydrogen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A possible approach is presented for evaluation of brain blood-flow changes registered by electrochemically generated hydrogen. Dynamics of cerebral blood flow (CBF) was studied in experiments on rats with implanted platinum electrodes. Using the experimental model of reversible brain death under hypoxic load, it was found that during one or several minutes before respiration interruption at 5-3% O2 in the experimental chamber CBF stabilizes at a new higher level. The ranges of CBF shifts were determined by hydrogen inhalation clearance measurements before and during hypoxic load (at 5-3% O2 in chamber). These data provide a correct comparison of cerebral blood-flow changes continually registered by different electrodes.

Original languageEnglish
Title of host publicationProceedings of the Annual Conference on Engineering in Medicine and Biology
PublisherPubl by IEEE
Pages309-310
Number of pages2
Editionpt 1
ISBN (Print)0780302168
StatePublished - 1991
Externally publishedYes
EventProceedings of the 13th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Orlando, FL, USA
Duration: Oct 31 1991Nov 3 1991

Publication series

NameProceedings of the Annual Conference on Engineering in Medicine and Biology
Numberpt 1
Volume13
ISSN (Print)0589-1019

Conference

ConferenceProceedings of the 13th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityOrlando, FL, USA
Period10/31/9111/3/91

ASJC Scopus Subject Areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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