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ASSESSING UNILATERAL ARM LYMPHEDEMA STATUS USING INTERARM TISSUE DIELECTRIC CONSTANT RATIOS

Research output: Contribution to journalArticlepeer-review

Abstract

Early detection of early-stage lymphedema resulting from breast cancer treatment enables prompt intervention and can potentially slow disease progression. To support this, various methods have been developed that use quantitative criteria sensitive to excess tissue fluid, which is a hallmark of lymphedema. One such method involves measuring the dielectric constant (TDC) of arm tissue in both the at-risk and contralateral arms to calculate their ratio. This communication aims to estimate what constitutes an interarm TDC ratio likely to serve as a threshold for arm lymphedema. Data from 403 healthy women were used to calculate the ratio of the highest to the lowest forearm TDC values (β). The distribution of β was analyzed, and estimated lymphedema thresholds were calculated as the mean β plus 2.0, 2.5, and 3.0 standard deviations, producing less and more conservative thresholds. Values ranged from approximately 1.15 to 1.20, with only 0.74% of cases exceeding a β value of 1.20. The β values were not affected by age, which ranged from 18 to 87, or body mass index, ranging from 14.7 to 49.9 kg/m2. These data represent the most comprehensive reference values available to help physicians and therapists determine appropriate thresholds.

Original languageEnglish
Pages (from-to)20-26
Number of pages7
JournalLymphology
Volume59
Issue number1
DOIs
StatePublished - Jan 2026

Bibliographical note

Publisher Copyright:
© (2026), (International Society of Lymphology). All rights reserved.

ASJC Scopus Subject Areas

  • Immunology and Allergy
  • Hematology

Keywords

  • Arm lymphedema thresholds
  • BCRL
  • Breast cancer-related lymphedema
  • Lymphedema detection
  • TDC
  • Tissue dielectric constant

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