Bacterial-derived biopolymers: Advanced natural nanomaterials for drug delivery and tissue engineering

Ahad Mokhtarzadeh; Abbas Alibakhshi; Maryam Hejazi; Yadollah Omidi; Jafar Ezzati Nazhad Dolatabadi

doi:10.1016/j.trac.2016.06.013

Bacterial-derived biopolymers: Advanced natural nanomaterials for drug delivery and tissue engineering

Ahad Mokhtarzadeh
, Abbas Alibakhshi
, Maryam Hejazi
, Yadollah Omidi
, Jafar Ezzati Nazhad Dolatabadi

Research output: Contribution to journal › Review article › peer-review

Abstract

There are several biocompatible and biodegradable biopolymers, which found tremendous medical and pharmaceutical applications and currently receiving unprecedented attention. Various microorganisms can synthesize a variety of these biopolymers such as polysaccharides, polyamides and polyesters, which could be used for development of new generation of drug carriers and tissue repairing materials. The size, charge, chemical structure and other physicochemical properties of bacterial biodegradable polymers represent a good compatibility in development of tissue scaffolds and also as delivery vehicles of therapeutic agents. Here, we highlight recent advances in engineering biopolymers derived from bacteria, especially for drug delivery and tissue engineering.

Original language	English
Pages (from-to)	367-384
Number of pages	18
Journal	TrAC - Trends in Analytical Chemistry
Volume	82
DOIs	https://doi.org/10.1016/j.trac.2016.06.013
State	Published - Sep 1 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2016 Elsevier B.V.

ASJC Scopus Subject Areas

Analytical Chemistry
Spectroscopy

Keywords

Biodegradable
Drug carrier
Nanomaterials
Polysaccharides
Tissue engineering

Access to Document

10.1016/j.trac.2016.06.013

Cite this

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abstract = "There are several biocompatible and biodegradable biopolymers, which found tremendous medical and pharmaceutical applications and currently receiving unprecedented attention. Various microorganisms can synthesize a variety of these biopolymers such as polysaccharides, polyamides and polyesters, which could be used for development of new generation of drug carriers and tissue repairing materials. The size, charge, chemical structure and other physicochemical properties of bacterial biodegradable polymers represent a good compatibility in development of tissue scaffolds and also as delivery vehicles of therapeutic agents. Here, we highlight recent advances in engineering biopolymers derived from bacteria, especially for drug delivery and tissue engineering.",

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T2 - Advanced natural nanomaterials for drug delivery and tissue engineering

AU - Mokhtarzadeh, Ahad

AU - Alibakhshi, Abbas

AU - Hejazi, Maryam

AU - Omidi, Yadollah

AU - Ezzati Nazhad Dolatabadi, Jafar

PY - 2016/9/1

Y1 - 2016/9/1

N2 - There are several biocompatible and biodegradable biopolymers, which found tremendous medical and pharmaceutical applications and currently receiving unprecedented attention. Various microorganisms can synthesize a variety of these biopolymers such as polysaccharides, polyamides and polyesters, which could be used for development of new generation of drug carriers and tissue repairing materials. The size, charge, chemical structure and other physicochemical properties of bacterial biodegradable polymers represent a good compatibility in development of tissue scaffolds and also as delivery vehicles of therapeutic agents. Here, we highlight recent advances in engineering biopolymers derived from bacteria, especially for drug delivery and tissue engineering.

AB - There are several biocompatible and biodegradable biopolymers, which found tremendous medical and pharmaceutical applications and currently receiving unprecedented attention. Various microorganisms can synthesize a variety of these biopolymers such as polysaccharides, polyamides and polyesters, which could be used for development of new generation of drug carriers and tissue repairing materials. The size, charge, chemical structure and other physicochemical properties of bacterial biodegradable polymers represent a good compatibility in development of tissue scaffolds and also as delivery vehicles of therapeutic agents. Here, we highlight recent advances in engineering biopolymers derived from bacteria, especially for drug delivery and tissue engineering.

KW - Biodegradable

KW - Drug carrier

KW - Nanomaterials

KW - Polysaccharides

KW - Tissue engineering

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DO - 10.1016/j.trac.2016.06.013

M3 - Review article

AN - SCOPUS:84977140452

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VL - 82

SP - 367

EP - 384

JO - TrAC - Trends in Analytical Chemistry

JF - TrAC - Trends in Analytical Chemistry

ER -

Bacterial-derived biopolymers: Advanced natural nanomaterials for drug delivery and tissue engineering

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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