Brain renin: localization in rat brain synaptosomal fractions

Ahsan Husain; Robert R. Smeby; Johanna Krontiris-Litowitz; Robert C. Speth

doi:10.1016/0006-8993(81)90956-2

Brain renin: localization in rat brain synaptosomal fractions

Ahsan Husain
, Robert R. Smeby
, Johanna Krontiris-Litowitz
, Robert C. Speth

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

The distribution of brain renin activity was determined in subcellular fractions of rat brain prepared by discontinuous density gradient centrifugation. The highest amounts of brain renin activity occurred in both the light and heavy synaptosomal fractions, while the activity of choline acetyltransferase was elevated only in the light synaptosomal fraction. These results indicate an intraneuronal localization of brain renin.

Original language	English
Pages (from-to)	182-186
Number of pages	5
Journal	Brain Research
Volume	222
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(81)90956-2
State	Published - Oct 5 1981
Externally published	Yes

ASJC Scopus Subject Areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

Keywords

brain renin
choline acetyltransferase
neuronal localization
synaptosomes

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10.1016/0006-8993(81)90956-2

Cite this

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title = "Brain renin: localization in rat brain synaptosomal fractions",

abstract = "The distribution of brain renin activity was determined in subcellular fractions of rat brain prepared by discontinuous density gradient centrifugation. The highest amounts of brain renin activity occurred in both the light and heavy synaptosomal fractions, while the activity of choline acetyltransferase was elevated only in the light synaptosomal fraction. These results indicate an intraneuronal localization of brain renin. ",

keywords = "brain renin, choline acetyltransferase, neuronal localization, synaptosomes",

author = "Ahsan Husain and Smeby, \{Robert R.\} and Johanna Krontiris-Litowitz and Speth, \{Robert C.\}",

year = "1981",

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doi = "10.1016/0006-8993(81)90956-2",

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journal = "Brain Research",

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T2 - localization in rat brain synaptosomal fractions

AU - Husain, Ahsan

AU - Smeby, Robert R.

AU - Krontiris-Litowitz, Johanna

AU - Speth, Robert C.

PY - 1981/10/5

Y1 - 1981/10/5

N2 - The distribution of brain renin activity was determined in subcellular fractions of rat brain prepared by discontinuous density gradient centrifugation. The highest amounts of brain renin activity occurred in both the light and heavy synaptosomal fractions, while the activity of choline acetyltransferase was elevated only in the light synaptosomal fraction. These results indicate an intraneuronal localization of brain renin.

AB - The distribution of brain renin activity was determined in subcellular fractions of rat brain prepared by discontinuous density gradient centrifugation. The highest amounts of brain renin activity occurred in both the light and heavy synaptosomal fractions, while the activity of choline acetyltransferase was elevated only in the light synaptosomal fraction. These results indicate an intraneuronal localization of brain renin.

KW - brain renin

KW - choline acetyltransferase

KW - neuronal localization

KW - synaptosomes

UR - https://www.scopus.com/pages/publications/0019873635

UR - https://www.scopus.com/pages/publications/0019873635#tab=citedBy

U2 - 10.1016/0006-8993(81)90956-2

DO - 10.1016/0006-8993(81)90956-2

M3 - Article

C2 - 7028209

AN - SCOPUS:0019873635

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SP - 182

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JF - Brain Research

IS - 1

ER -

Brain renin: localization in rat brain synaptosomal fractions

Abstract

ASJC Scopus Subject Areas

Keywords

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