TY - JOUR
T1 - Cognitive-behavioral stress management decreases dysphoric mood and herpes simplex virus-type 2 antibody titers in symptomatic HIV-seropositive gay men
AU - Lutgendorf, Susan K.
AU - Antoni, Michael H.
AU - Ironson, Gail
AU - Klimas, Nancy
AU - Kumar, Mahendra
AU - Starr, Kathleen
AU - McCabe, Philip
AU - Cleven, Karen
AU - Fletcher, Mary Ann
AU - Schneiderman, Neil
PY - 1997/2
Y1 - 1997/2
N2 - This study tested the effects of a 10-week group cognitive behavioral stress management (CBSM) intervention on mood and immunologic parameters in HIV-seropositive gay men whose disease had progressed to a symptomatic stage. Men were randomized to either CBSM or a modified waiting list control group. The CBSM intervention significantly decreased self-reported dysphoria, anxiety, and total distress. Individuals who practiced relaxation more consistently had significantly greater drops in dysphoria. The intervention also decreased herpes simplex virus-Type 2 (HSV-2) immunoglobulin G antibody titers. The control group showed no significant changes in either mood or antibody titers. Individual difference analyses revealed that decreases in dysphoria significantly predicted lower HSV-2 antibody titers by the end of the 10-week period. Neither group displayed changes in HSV-Type 1 antibody titers or in CD4+ or CD8+ cell numbers.
AB - This study tested the effects of a 10-week group cognitive behavioral stress management (CBSM) intervention on mood and immunologic parameters in HIV-seropositive gay men whose disease had progressed to a symptomatic stage. Men were randomized to either CBSM or a modified waiting list control group. The CBSM intervention significantly decreased self-reported dysphoria, anxiety, and total distress. Individuals who practiced relaxation more consistently had significantly greater drops in dysphoria. The intervention also decreased herpes simplex virus-Type 2 (HSV-2) immunoglobulin G antibody titers. The control group showed no significant changes in either mood or antibody titers. Individual difference analyses revealed that decreases in dysphoria significantly predicted lower HSV-2 antibody titers by the end of the 10-week period. Neither group displayed changes in HSV-Type 1 antibody titers or in CD4+ or CD8+ cell numbers.
UR - https://www.scopus.com/pages/publications/0031037657
UR - https://www.scopus.com/pages/publications/0031037657#tab=citedBy
U2 - 10.1037/0022-006X.65.1.31
DO - 10.1037/0022-006X.65.1.31
M3 - Article
C2 - 9103732
AN - SCOPUS:0031037657
SN - 0022-006X
VL - 65
SP - 31
EP - 43
JO - Journal of Consulting and Clinical Psychology
JF - Journal of Consulting and Clinical Psychology
IS - 1
ER -