“Common questions and misconceptions about dietary supplements and the industry - What does science and the law really say?“

  • Jose Antonio
  • , Brandi Antonio
  • , Alan Aragon
  • , Erik Bustillo
  • , Darren Candow
  • , Rick Collins
  • , Edwin Davila
  • , Bob Durkin
  • , Douglas Kalman
  • , Chris Lockwood
  • , Scotty Mills
  • , Jeffrey R. Stout

Research output: Contribution to journalReview articlepeer-review

Abstract

Dietary supplement use is popular among fitness enthusiasts as well as competitive athletes. There is, however, confusion regarding the regulatory framework as well as the basic science regarding the use of supplements. Although there is an extensive body of scientific and legal writings on dietary supplements, several misconceptions persist vis-à-vis this category. Thus, the following questions will be addressed in this review. 1) Are dietary supplements regulated by the Food and Drug Administration? 2) Are foods and supplements regulated similarly? 3) What is the role of the Federal Trade Commission? 4) Besides federal regulations for dietary supplements, do state laws also regulate the category? 5) If a supplement company funds a study, does that automatically call into question the results? 6) Can diet alone provide everything you need without using supplements? 7) Is it necessary to conduct randomized controlled trials (RCTs) on dietary supplements? 8) How safe are supplements compared to OTC drugs? 9) Where can consumers find accurate information about supplements? 10) Why does the NIH fund dietary supplement research related to disease, yet findings cannot be marketed by supplement companies? 11) What is the size of the dietary supplement industry compared to the pharmaceutical industry? 12) How can I know if a dietary supplement is safe and free of banned substances? Similar to our prior papers, a team of legal and science scholars evaluated the evidence on these salient questions.

Original languageEnglish
Article number2534128
Pages (from-to)2534128
JournalJournal of the International Society of Sports Nutrition
Volume22
Issue number1
DOIs
StatePublished - Jul 15 2025

Bibliographical note

Publisher Copyright:
© 2025 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Funding

The author(s) reported there is no funding associated with the work featured in this article.

ASJC Scopus Subject Areas

  • Food Science
  • Nutrition and Dietetics

Keywords

  • FDA
  • nutrition
  • regulation
  • safety
  • Social media

Disciplines

  • Food Science
  • Nutrition
  • Dietetics and Clinical Nutrition

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