Comparison of intravenous anesthetic agents for the treatment of refractory status epilepticus

Michael E. Reznik; Karen Berger; Jan Claassen

doi:10.3390/jcm5050054

Comparison of intravenous anesthetic agents for the treatment of refractory status epilepticus

Michael E. Reznik
, Karen Berger
, Jan Claassen

Research output: Contribution to journal › Review article › peer-review

Abstract

Status epilepticus that cannot be controlled with first- and second-line agents is called refractory status epilepticus (RSE), a condition that is associated with significant morbidity and mortality. Most experts agree that treatment of RSE necessitates the use of continuous infusion intravenous anesthetic drugs such as midazolam, propofol, pentobarbital, thiopental, and ketamine, each of which has its own unique characteristics. This review compares the various anesthetic agents while providing an approach to their use in adult patients, along with possible associated complications.

Original language	English
Article number	54
Journal	Journal of Clinical Medicine
Volume	5
Issue number	5
DOIs	https://doi.org/10.3390/jcm5050054
State	Published - May 1 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2016 by the authors; licensee MDPI, Basel, Switzerland.

ASJC Scopus Subject Areas

General Medicine

Keywords

IV anesthetics
Refractory status epilepticus
Status epilepticus

Access to Document

10.3390/jcm5050054

Cite this

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abstract = "Status epilepticus that cannot be controlled with first- and second-line agents is called refractory status epilepticus (RSE), a condition that is associated with significant morbidity and mortality. Most experts agree that treatment of RSE necessitates the use of continuous infusion intravenous anesthetic drugs such as midazolam, propofol, pentobarbital, thiopental, and ketamine, each of which has its own unique characteristics. This review compares the various anesthetic agents while providing an approach to their use in adult patients, along with possible associated complications.",

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AU - Berger, Karen

AU - Claassen, Jan

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N2 - Status epilepticus that cannot be controlled with first- and second-line agents is called refractory status epilepticus (RSE), a condition that is associated with significant morbidity and mortality. Most experts agree that treatment of RSE necessitates the use of continuous infusion intravenous anesthetic drugs such as midazolam, propofol, pentobarbital, thiopental, and ketamine, each of which has its own unique characteristics. This review compares the various anesthetic agents while providing an approach to their use in adult patients, along with possible associated complications.

AB - Status epilepticus that cannot be controlled with first- and second-line agents is called refractory status epilepticus (RSE), a condition that is associated with significant morbidity and mortality. Most experts agree that treatment of RSE necessitates the use of continuous infusion intravenous anesthetic drugs such as midazolam, propofol, pentobarbital, thiopental, and ketamine, each of which has its own unique characteristics. This review compares the various anesthetic agents while providing an approach to their use in adult patients, along with possible associated complications.

KW - IV anesthetics

KW - Refractory status epilepticus

KW - Status epilepticus

UR - https://www.scopus.com/pages/publications/85015915225

UR - https://www.scopus.com/pages/publications/85015915225#tab=citedBy

U2 - 10.3390/jcm5050054

DO - 10.3390/jcm5050054

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AN - SCOPUS:85015915225

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JO - Journal of Clinical Medicine

JF - Journal of Clinical Medicine

IS - 5

M1 - 54

ER -

Comparison of intravenous anesthetic agents for the treatment of refractory status epilepticus

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Access to Document

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Cite this