Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers

Ali Pourali; Yadollah Omidi

doi:10.34172/bi.2023.22023

Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers

Ali Pourali
, Yadollah Omidi

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The molecular marker, cardiac troponin (cTn) is a complex protein that is attached to tropomyosin on the actin filament. It is an essential biomolecule in terms of the calcium-mediated regulation of the contractile apparatus in myofibrils, the release of which is an indication of the dysfunction of cardiomyocytes and hence the initiation of ischemic phenomena in the heart tissue. Fast and accurate analysis of cTn may help the diagnosis and management of acute myocardial infarction (AMI), for which electrochemical biosensors and microfluidics devices can be of great benefit. This editorial aims to highlight the importance of cTn as vital biomarkers in AMI diagnosis.

Original language	English
Pages (from-to)	85-88
Number of pages	4
Journal	BioImpacts
Volume	13
Issue number	2
DOIs	https://doi.org/10.34172/bi.2023.22023
State	Published - Mar 2023

Bibliographical note

Publisher Copyright:
© 2023 The Author(s). This work is published by BioImpacts as an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.

ASJC Scopus Subject Areas

General Biochemistry,Genetics and Molecular Biology
Pharmaceutical Science

Keywords

Acute myocardial infarction
Biosensor
Cardiac troponin
Cardiomyocytes
Electrochemical analysis
Microfluidics

Disciplines

Biochemistry
Pharmacy and Pharmaceutical Sciences

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10.34172/bi.2023.22023License: CC BY-NC

bi-13-85Final published version, 668 KBLicense: CC BY-NC

Cite this

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title = "Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers",

abstract = "The molecular marker, cardiac troponin (cTn) is a complex protein that is attached to tropomyosin on the actin filament. It is an essential biomolecule in terms of the calcium-mediated regulation of the contractile apparatus in myofibrils, the release of which is an indication of the dysfunction of cardiomyocytes and hence the initiation of ischemic phenomena in the heart tissue. Fast and accurate analysis of cTn may help the diagnosis and management of acute myocardial infarction (AMI), for which electrochemical biosensors and microfluidics devices can be of great benefit. This editorial aims to highlight the importance of cTn as vital biomarkers in AMI diagnosis.",

keywords = "Acute myocardial infarction, Biosensor, Cardiac troponin, Cardiomyocytes, Electrochemical analysis, Microfluidics",

author = "Ali Pourali and Yadollah Omidi",

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year = "2023",

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doi = "10.34172/bi.2023.22023",

language = "English",

volume = "13",

pages = "85--88",

journal = "BioImpacts",

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publisher = "Tabriz University of Medical Sciences",

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TY - JOUR

T1 - Diagnosis of acute myocardial infarction

T2 - highlighting cardiac troponins as vital biomarkers

AU - Pourali, Ali

AU - Omidi, Yadollah

N1 - Publisher Copyright: © 2023 The Author(s). This work is published by BioImpacts as an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.

PY - 2023/3

Y1 - 2023/3

N2 - The molecular marker, cardiac troponin (cTn) is a complex protein that is attached to tropomyosin on the actin filament. It is an essential biomolecule in terms of the calcium-mediated regulation of the contractile apparatus in myofibrils, the release of which is an indication of the dysfunction of cardiomyocytes and hence the initiation of ischemic phenomena in the heart tissue. Fast and accurate analysis of cTn may help the diagnosis and management of acute myocardial infarction (AMI), for which electrochemical biosensors and microfluidics devices can be of great benefit. This editorial aims to highlight the importance of cTn as vital biomarkers in AMI diagnosis.

AB - The molecular marker, cardiac troponin (cTn) is a complex protein that is attached to tropomyosin on the actin filament. It is an essential biomolecule in terms of the calcium-mediated regulation of the contractile apparatus in myofibrils, the release of which is an indication of the dysfunction of cardiomyocytes and hence the initiation of ischemic phenomena in the heart tissue. Fast and accurate analysis of cTn may help the diagnosis and management of acute myocardial infarction (AMI), for which electrochemical biosensors and microfluidics devices can be of great benefit. This editorial aims to highlight the importance of cTn as vital biomarkers in AMI diagnosis.

KW - Acute myocardial infarction

KW - Biosensor

KW - Cardiac troponin

KW - Cardiomyocytes

KW - Electrochemical analysis

KW - Microfluidics

UR - https://www.scopus.com/pages/publications/85152106674

UR - https://www.scopus.com/pages/publications/85152106674#tab=citedBy

U2 - 10.34172/bi.2023.22023

DO - 10.34172/bi.2023.22023

M3 - Article

AN - SCOPUS:85152106674

SN - 2228-5652

VL - 13

SP - 85

EP - 88

JO - BioImpacts

JF - BioImpacts

IS - 2

ER -

Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

Disciplines

Access to Document

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