Dynamic aphasia as a variant of frontotemporal dementia

  • Adithya Chandregowda
  • , Heather M. Clark
  • , Joseph R. Duffy
  • , Mary M. Machulda
  • , Val J. Lowe
  • , Jennifer L. Whitwell
  • , Keith A. Josephs

Research output: Contribution to journalArticlepeer-review

Abstract

We describe two individuals with progressive verbal difficulty who exhibited impairment of propositional language, with relatively well-preserved auditory comprehension, naming, and repetition -a profile that is consistent with dynamic aphasia. By providing a brief review of pertinent literature and the results from our neurologic, speech and language, neuropsychological, and neuroimaging testing, this report sheds light on the infrequently reported dynamic aphasia in the context of frontotemporal dementia. Our patients' insights into their verbal difficulty tend to support the notion that dynamic aphasia results from interference at the stage where thoughts are converted into verbal messages-that is, the thought-verbal interface.

Original languageEnglish
Pages (from-to)303-318
Number of pages16
JournalCognitive and Behavioral Neurology
Volume34
Issue number4
DOIs
StatePublished - Dec 2 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2021 Lippincott Williams and Wilkins. All rights reserved.

ASJC Scopus Subject Areas

  • Neuropsychology and Physiological Psychology
  • Cognitive Neuroscience
  • Psychiatry and Mental health

Keywords

  • Dynamic aphasia
  • Frontotemporal dementia
  • Left frontal lobe
  • Primary progressive aphasia
  • Propositional language
  • Neuropsychological Tests
  • Aphasia/diagnosis
  • Humans
  • Frontotemporal Dementia/diagnostic imaging
  • Speech
  • Comprehension

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