Effect of suboptimal breast-feeding on occurrence of autism: A case-control study

Yahya M. Al-Farsi; Marwan M. Al-Sharbati; Mostafa I. Waly; Omar A. Al-Farsi; Mohammed A. Al-Shafaee; Maha M. Al-Khaduri; Malav S. Trivedi; Richard C. Deth

doi:10.1016/j.nut.2012.01.007

Effect of suboptimal breast-feeding on occurrence of autism: A case-control study

Yahya M. Al-Farsi
, Marwan M. Al-Sharbati
, Mostafa I. Waly
, Omar A. Al-Farsi
, Mohammed A. Al-Shafaee
, Maha M. Al-Khaduri
, Malav S. Trivedi
, Richard C. Deth

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: To evaluate the association between suboptimal breast-feeding practices and autism spectrum disorders (ASDs). Methods: A case-control study was conducted in 102 ASD cases and 102 matched healthy controls. Results: Based on adjusted odds ratios from logistic regression models, ASD was found to be associated with the late initiation of breast-feeding (odds ratio 1.48, 95% confidence interval 1.01-3.1), a non-intake of colostrum (odds ratio 1.7, 95% confidence interval 1.03-4.3), prelacteal feeding, and bottle-feeding. The risk of ASD was found to decrease in a dose-response fashion over increasing periods of exclusive breast-feeding (P for trend = 0.04) and continued breast-feeding (P for trend = 0.001). Conclusion: The study indicates that increased ASD risk is generally associated with suboptimal breast-feeding practices.

Original language	English
Pages (from-to)	e27-e32
Journal	Nutrition
Volume	28
Issue number	7-8
DOIs	https://doi.org/10.1016/j.nut.2012.01.007
State	Published - Jul 2012
Externally published	Yes

Bibliographical note

ASJC Scopus Subject Areas

Endocrinology, Diabetes and Metabolism
Nutrition and Dietetics

Keywords

Autism
Autism spectrum disorder
Oman
Suboptimal breast-feeding
Diagnostic and Statistical Manual of Mental Disorders
Breast Feeding/ethnology
Humans
Hospitals, University
Child, Preschool
Logistic Models
Male
Risk
Case-Control Studies
Pilot Projects
Child Health Services
Oman/epidemiology
Adolescent
Child Development Disorders, Pervasive/epidemiology
Female
Surveys and Questionnaires
Child Development
Colostrum
Outpatient Clinics, Hospital
Child

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10.1016/j.nut.2012.01.007

Cite this

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title = "Effect of suboptimal breast-feeding on occurrence of autism: A case-control study",

abstract = "Objective: To evaluate the association between suboptimal breast-feeding practices and autism spectrum disorders (ASDs). Methods: A case-control study was conducted in 102 ASD cases and 102 matched healthy controls. Results: Based on adjusted odds ratios from logistic regression models, ASD was found to be associated with the late initiation of breast-feeding (odds ratio 1.48, 95\% confidence interval 1.01-3.1), a non-intake of colostrum (odds ratio 1.7, 95\% confidence interval 1.03-4.3), prelacteal feeding, and bottle-feeding. The risk of ASD was found to decrease in a dose-response fashion over increasing periods of exclusive breast-feeding (P for trend = 0.04) and continued breast-feeding (P for trend = 0.001). Conclusion: The study indicates that increased ASD risk is generally associated with suboptimal breast-feeding practices. ",

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author = "Al-Farsi, \{Yahya M.\} and Al-Sharbati, \{Marwan M.\} and Waly, \{Mostafa I.\} and Al-Farsi, \{Omar A.\} and Al-Shafaee, \{Mohammed A.\} and Al-Khaduri, \{Maha M.\} and Trivedi, \{Malav S.\} and Deth, \{Richard C.\}",

year = "2012",

month = jul,

doi = "10.1016/j.nut.2012.01.007",

language = "English",

volume = "28",

pages = "e27--e32",

journal = "Nutrition",

issn = "0899-9007",

number = "7-8",

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T2 - A case-control study

AU - Al-Farsi, Yahya M.

AU - Al-Sharbati, Marwan M.

AU - Waly, Mostafa I.

AU - Al-Farsi, Omar A.

AU - Al-Shafaee, Mohammed A.

AU - Al-Khaduri, Maha M.

AU - Trivedi, Malav S.

AU - Deth, Richard C.

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AB - Objective: To evaluate the association between suboptimal breast-feeding practices and autism spectrum disorders (ASDs). Methods: A case-control study was conducted in 102 ASD cases and 102 matched healthy controls. Results: Based on adjusted odds ratios from logistic regression models, ASD was found to be associated with the late initiation of breast-feeding (odds ratio 1.48, 95% confidence interval 1.01-3.1), a non-intake of colostrum (odds ratio 1.7, 95% confidence interval 1.03-4.3), prelacteal feeding, and bottle-feeding. The risk of ASD was found to decrease in a dose-response fashion over increasing periods of exclusive breast-feeding (P for trend = 0.04) and continued breast-feeding (P for trend = 0.001). Conclusion: The study indicates that increased ASD risk is generally associated with suboptimal breast-feeding practices.

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KW - Surveys and Questionnaires

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KW - Colostrum

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ER -

Effect of suboptimal breast-feeding on occurrence of autism: A case-control study

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Keywords

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