Evolution of mammalian genome organization inferred from comparative gene mapping

  • W. J. Murphy
  • , R. Stanyon
  • , S. J. O'Brien
  • , Stephen James O'Brien

Research output: Contribution to journalArticlepeer-review

Abstract

Comparative genome analyses, including chromosome painting in over 40 diverse mammalian species, ordered gene maps from several representatives of different mammalian and vertebrate orders, and large-scale sequencing of the human and mouse genomes are beginning to provide insight into the rates and patterns of chromosomal evolution on a whole-genome scale, as well as into the forces that have sculpted the genomes of extant mammalian species.

Original languageAmerican English
JournalGenome Biology
Volume2
Issue number6
StatePublished - Jan 1 2001

ASJC Scopus Subject Areas

  • Genetics
  • Ecology, Evolution, Behavior and Systematics
  • Cell Biology

Disciplines

  • Genetics and Genomics
  • Life Sciences

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