Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open
field test of anxiety while increasing plasma corticosterone levels

Jaime L. Tartar; C.P. Ward; J.W. Cordeira; S.L. Legare; A.J. Blanchette; R.W. McCarley; R.E. Strecker

doi:10.1016/j.bbr.2008.08.035

Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels

Jaime L. Tartar
, C.P. Ward
, J.W. Cordeira
, S.L. Legare
, A.J. Blanchette
, R.W. McCarley
, R.E. Strecker

College of Psychology

Research output: Contribution to journal › Article › peer-review

Abstract

Sleep deprivation alters mood and anxiety in man. In rats, 24 h of treadmill-induced total sleep deprivation or sleep fragmentation increased exploratory behavior in an open field test of anxiety compared to cage or exercise controls. Plasma corticosterone (CORT) levels of sleep disturbed and exercise control rats were elevated compared to cage controls, suggesting that the increased exploration observed in the sleep disturbed rats was not due to a hypothalamic-pituitary-adrenal (HPA) stress response.

Original language	American English
Journal	Behav Brain Res
Volume	197
DOIs	https://doi.org/10.1016/j.bbr.2008.08.035
State	Published - Jan 1 2009

Disciplines

Psychology

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title = "Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels",

abstract = " Sleep deprivation alters mood and anxiety in man. In rats, 24 h of treadmill-induced total sleep deprivation or sleep fragmentation increased exploratory behavior in an open field test of anxiety compared to cage or exercise controls. Plasma corticosterone (CORT) levels of sleep disturbed and exercise control rats were elevated compared to cage controls, suggesting that the increased exploration observed in the sleep disturbed rats was not due to a hypothalamic-pituitary-adrenal (HPA) stress response.",

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T1 - Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels

AU - Tartar, Jaime L.

AU - Ward, C.P.

AU - Cordeira, J.W.

AU - Legare, S.L.

AU - Blanchette, A.J.

AU - McCarley, R.W.

AU - Strecker, R.E.

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Sleep deprivation alters mood and anxiety in man. In rats, 24 h of treadmill-induced total sleep deprivation or sleep fragmentation increased exploratory behavior in an open field test of anxiety compared to cage or exercise controls. Plasma corticosterone (CORT) levels of sleep disturbed and exercise control rats were elevated compared to cage controls, suggesting that the increased exploration observed in the sleep disturbed rats was not due to a hypothalamic-pituitary-adrenal (HPA) stress response.

AB - Sleep deprivation alters mood and anxiety in man. In rats, 24 h of treadmill-induced total sleep deprivation or sleep fragmentation increased exploratory behavior in an open field test of anxiety compared to cage or exercise controls. Plasma corticosterone (CORT) levels of sleep disturbed and exercise control rats were elevated compared to cage controls, suggesting that the increased exploration observed in the sleep disturbed rats was not due to a hypothalamic-pituitary-adrenal (HPA) stress response.

UR - https://nsuworks.nova.edu/cps_facarticles/1203

U2 - 10.1016/j.bbr.2008.08.035

DO - 10.1016/j.bbr.2008.08.035

M3 - Article

C2 - 18805441

VL - 197

JO - Behav Brain Res

JF - Behav Brain Res

ER -

Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels

Abstract

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