Gaining a solid grip on adipogenesis

  • M. E. Fernyhough
  • , L. R. Bucci
  • , G. J. Hausman
  • , Jose Antonio
  • , J. L. Vierck
  • , M. V. Dodson

Research output: Contribution to journalArticlepeer-review

Abstract

Obesity is presently being combated by fitness regimens, drugs and diet. Increasing our understanding of the physiology of adipocytes, by deducing the regulatory pathways involved in lipid metabolism and all aspects of adipogenesis, will provide alternative strategies to reduce adverse problems of obesity. Research has suggested that mature fat cells may dedifferentiate to form proliferative-competent fat cell precursors. Knowledge of the dedifferentiation process will allow us to gain a solid grip on adipogenesis.

Original languageAmerican English
Pages (from-to)335-338
Number of pages4
JournalTissue & Cell
Volume37
Issue number4
StatePublished - Aug 1 2005

Funding

This research is presently supported by the Cooperative State Research, Education, and Extension Service; U.S. Department of Agriculture, under Agreement Nos. 2002-38879-01985, 2003-38879-02091, 2003-352606-12880 and 2003-34468-14085; by Weider Nutrition, International; and by the Washington State Agricultural Research Center, Project 0913. MVD is a participant of U.S.D.A. Regional Research Project NC-131, “Molecular Mechanisms Regulating Skeletal Muscle Growth and Differentiation.”

FundersFunder number
Washington State Agricultural Research Center
U.S. Department of Agriculture2003-352606-12880, 2002-38879-01985, 2003-34468-14085, 2003-38879-02091
Cooperative State Research, Education, and Extension Service

    ASJC Scopus Subject Areas

    • Developmental Biology
    • Cell Biology

    Keywords

    • Dedifferentiation
    • Mature adipocytes

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