TY - JOUR
T1 - IL-34 a newly discovered cytokine
AU - Castellani, Maria Luisa
AU - Anogeianaki, A.
AU - Felaco, P.
AU - Toniato, E.
AU - De Lutiis, M. A.
AU - Shaik, B.
AU - Fulcheri, M.
AU - Vecchiet, J.
AU - Tetè, S.
AU - Salini, V.
AU - Theoharides, T. C.
AU - Caraffa, A.
AU - Antinolfi, P.
AU - Frydas, S.
AU - Conti, P.
AU - Cuccurullo, C.
AU - Ciampoli, C.
AU - Cerulli, G.
PY - 2010
Y1 - 2010
N2 - In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that 11-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.
AB - In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that 11-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.
KW - Cell differentiation
KW - Cytokine antagonists
KW - Interleukin-34
KW - Monocytes
UR - https://www.scopus.com/pages/publications/77957930030
UR - https://www.scopus.com/pages/publications/77957930030#tab=citedBy
U2 - 10.1177/1721727X1000800202
DO - 10.1177/1721727X1000800202
M3 - Review article
AN - SCOPUS:77957930030
SN - 1721-727X
VL - 8
SP - 63
EP - 66
JO - European Journal of Inflammation
JF - European Journal of Inflammation
IS - 2
ER -