IL-34 a newly discovered cytokine

Maria Luisa Castellani; A. Anogeianaki; P. Felaco; E. Toniato; M. A. De Lutiis; B. Shaik; M. Fulcheri; J. Vecchiet; S. Tetè; V. Salini; T. C. Theoharides; A. Caraffa; P. Antinolfi; S. Frydas; P. Conti; C. Cuccurullo; C. Ciampoli; G. Cerulli

doi:10.1177/1721727X1000800202

IL-34 a newly discovered cytokine

Maria Luisa Castellani
, A. Anogeianaki
, P. Felaco
, E. Toniato
, M. A. De Lutiis
, B. Shaik
, M. Fulcheri
, J. Vecchiet
, S. Tetè
, V. Salini
, T. C. Theoharides
, A. Caraffa
, P. Antinolfi
, S. Frydas
, P. Conti
, C. Cuccurullo
, C. Ciampoli
, G. Cerulli

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that 11-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.

Original language	English
Pages (from-to)	63-66
Number of pages	4
Journal	European Journal of Inflammation
Volume	8
Issue number	2
DOIs	https://doi.org/10.1177/1721727X1000800202
State	Published - 2010
Externally published	Yes

ASJC Scopus Subject Areas

Immunology and Allergy
Immunology

Keywords

Cell differentiation
Cytokine antagonists
Interleukin-34
Monocytes

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10.1177/1721727X1000800202

Cite this

Castellani, M. L., Anogeianaki, A., Felaco, P., Toniato, E., De Lutiis, M. A., Shaik, B., Fulcheri, M., Vecchiet, J., Tetè, S., Salini, V., Theoharides, T. C., Caraffa, A., Antinolfi, P., Frydas, S., Conti, P., Cuccurullo, C., Ciampoli, C., & Cerulli, G. (2010). IL-34 a newly discovered cytokine. European Journal of Inflammation, 8(2), 63-66. https://doi.org/10.1177/1721727X1000800202

Castellani, ML, Anogeianaki, A, Felaco, P, Toniato, E, De Lutiis, MA, Shaik, B, Fulcheri, M, Vecchiet, J, Tetè, S, Salini, V, Theoharides, TC, Caraffa, A, Antinolfi, P, Frydas, S, Conti, P, Cuccurullo, C, Ciampoli, C & Cerulli, G 2010, 'IL-34 a newly discovered cytokine', European Journal of Inflammation, vol. 8, no. 2, pp. 63-66. https://doi.org/10.1177/1721727X1000800202

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title = "IL-34 a newly discovered cytokine",

abstract = "In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that 11-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.",

keywords = "Cell differentiation, Cytokine antagonists, Interleukin-34, Monocytes",

author = "Castellani, \{Maria Luisa\} and A. Anogeianaki and P. Felaco and E. Toniato and \{De Lutiis\}, \{M. A.\} and B. Shaik and M. Fulcheri and J. Vecchiet and S. Tet{\`e} and V. Salini and Theoharides, \{T. C.\} and A. Caraffa and P. Antinolfi and S. Frydas and P. Conti and C. Cuccurullo and C. Ciampoli and G. Cerulli",

year = "2010",

doi = "10.1177/1721727X1000800202",

language = "English",

volume = "8",

pages = "63--66",

journal = "European Journal of Inflammation",

issn = "1721-727X",

publisher = "SAGE Publications Inc.",

number = "2",

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TY - JOUR

T1 - IL-34 a newly discovered cytokine

AU - Castellani, Maria Luisa

AU - Anogeianaki, A.

AU - Felaco, P.

AU - Toniato, E.

AU - De Lutiis, M. A.

AU - Shaik, B.

AU - Fulcheri, M.

AU - Vecchiet, J.

AU - Tetè, S.

AU - Salini, V.

AU - Theoharides, T. C.

AU - Caraffa, A.

AU - Antinolfi, P.

AU - Frydas, S.

AU - Conti, P.

AU - Cuccurullo, C.

AU - Ciampoli, C.

AU - Cerulli, G.

PY - 2010

Y1 - 2010

N2 - In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that 11-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.

AB - In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that 11-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.

KW - Cell differentiation

KW - Cytokine antagonists

KW - Interleukin-34

KW - Monocytes

UR - https://www.scopus.com/pages/publications/77957930030

UR - https://www.scopus.com/pages/publications/77957930030#tab=citedBy

U2 - 10.1177/1721727X1000800202

DO - 10.1177/1721727X1000800202

M3 - Review article

AN - SCOPUS:77957930030

SN - 1721-727X

VL - 8

SP - 63

EP - 66

JO - European Journal of Inflammation

JF - European Journal of Inflammation

IS - 2

ER -

IL-34 a newly discovered cytokine

Abstract

ASJC Scopus Subject Areas

Keywords

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