IL-36 a new member of the IL-1 family cytokines

Domenico Tripodi; F. Conti; M. Rosati; G. Maccauro; A. Saggini; E. Cianchetti; D. Angelucci; M. Fulcheri; S. Tetè; V. Salini; A. Caraffa; P. Antinolfi; E. Toniato; M. L. Castellani; P. Conti; T. C. Theoharides

IL-36 a new member of the IL-1 family cytokines

Domenico Tripodi
, F. Conti
, M. Rosati
, G. Maccauro
, A. Saggini
, E. Cianchetti
, D. Angelucci
, M. Fulcheri
, S. Tetè
, V. Salini
, A. Caraffa
, P. Antinolfi
, E. Toniato
, M. L. Castellani
, P. Conti
, T. C. Theoharides

Research output: Contribution to journal › Review article › peer-review

Abstract

Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity. IL-36 activates MAPK and NF-KB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. Here we summarise and review the new aspects of this important pro-inflammatory cytokine.

Original language	English
Pages (from-to)	7-14
Number of pages	8
Journal	Journal of biological regulators and homeostatic agents
Volume	26
Issue number	1
State	Published - Jan 2012
Externally published	Yes

ASJC Scopus Subject Areas

Endocrinology, Diabetes and Metabolism
Immunology and Allergy
Physiology
Immunology
Oncology
Endocrinology
Physiology (medical)
Cancer Research

Keywords

Cytokines
IL-36
Immunity
Inflammation
Interleukins

Cite this

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title = "IL-36 a new member of the IL-1 family cytokines",

abstract = "Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity. IL-36 activates MAPK and NF-KB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. Here we summarise and review the new aspects of this important pro-inflammatory cytokine.",

keywords = "Cytokines, IL-36, Immunity, Inflammation, Interleukins",

author = "Domenico Tripodi and F. Conti and M. Rosati and G. Maccauro and A. Saggini and E. Cianchetti and D. Angelucci and M. Fulcheri and S. Tet{\`e} and V. Salini and A. Caraffa and P. Antinolfi and E. Toniato and Castellani, \{M. L.\} and P. Conti and Theoharides, \{T. C.\}",

year = "2012",

month = jan,

language = "English",

volume = "26",

pages = "7--14",

journal = "Journal of biological regulators and homeostatic agents",

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TY - JOUR

T1 - IL-36 a new member of the IL-1 family cytokines

AU - Tripodi, Domenico

AU - Conti, F.

AU - Rosati, M.

AU - Maccauro, G.

AU - Saggini, A.

AU - Cianchetti, E.

AU - Angelucci, D.

AU - Fulcheri, M.

AU - Tetè, S.

AU - Salini, V.

AU - Caraffa, A.

AU - Antinolfi, P.

AU - Toniato, E.

AU - Castellani, M. L.

AU - Conti, P.

AU - Theoharides, T. C.

PY - 2012/1

Y1 - 2012/1

N2 - Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity. IL-36 activates MAPK and NF-KB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. Here we summarise and review the new aspects of this important pro-inflammatory cytokine.

AB - Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity. IL-36 activates MAPK and NF-KB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. Here we summarise and review the new aspects of this important pro-inflammatory cytokine.

KW - Cytokines

KW - IL-36

KW - Immunity

KW - Inflammation

KW - Interleukins

UR - https://www.scopus.com/pages/publications/84859918052

UR - https://www.scopus.com/pages/publications/84859918052#tab=citedBy

M3 - Review article

C2 - 22475093

AN - SCOPUS:84859918052

SN - 0393-974X

VL - 26

SP - 7

EP - 14

JO - Journal of biological regulators and homeostatic agents

JF - Journal of biological regulators and homeostatic agents

IS - 1

ER -

IL-36 a new member of the IL-1 family cytokines

Abstract

ASJC Scopus Subject Areas

Keywords

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