Interoceptive mechanisms of a mobile heart rate variability biofeedback app for eating disorder symptoms: Proof-of-concept findings

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Abstract

Introduction: Recent US-based datasets (Ns > 1000) show over 1-in-4 adults suffer from clinically significant eating disorder (ED) symptoms. Methods for preventing subthreshold problems from becoming full-threshold EDs are needed. An 8-week, single-arm feasibility study of a mobile heart rate variability biofeedback (HRVB) app supported strong acceptability and preliminary efficacy for reducing ED symptoms. The present study investigated potential mechanisms of change from pre- to post-intervention. Method: Participants were 24 healthcare workers recruited during the COVID-19 pandemic who scored in the clinically significant range on the Loss of Control Eating Scale-Brief (LOCES-Brief) (92 % female, 83 % non-Hispanic white, Mean age = 42; SD = 11.8). Measures included the eight subscales from the Multidimensional Assessment of Interoceptive Awareness-2 (MAIA-2) for interoceptive sensibility, and the Eating Disorder Examination-Questionnaire 7-item Short (EDE-Q7) and LOCES-Brief for ED symptoms. Mediation analyses were conducted using the MEMORE macro for repeated measures, with indirect effects evaluated via 95 % Monte Carlo confidence intervals. Results: Significant indirect effects on EDE-Q7 scores were found for MAIA-2 ‘noticing’, ‘attention-regulation’, ‘emotional-awareness’, ‘self-regulation’, and ‘body-listening’ subscales. ‘Not-worrying’, ‘not-distracting’, and ‘trusting’ did not significantly mediate EDE-Q7 changes. For LOCES-Brief, significant indirect effects were found for ‘trusting’. No other MAIA-2 subscales showed statistically significant indirect effects for LOCES-Brief. Conclusion: Findings suggest HRV biofeedback may reduce ED symptoms by enhancing interoceptive skills. These results support further investigation into biofeedback as a low-cost, scalable intervention for populations at risk for EDs. Future studies should evaluate fully powered controlled efficacy trials of mobile HRVB as a preventive strategy for eating and body-related mental health concerns.

Original languageEnglish
Article number102060
JournalEating Behaviors
Volume60
DOIs
StatePublished - Jan 2026

Bibliographical note

Publisher Copyright:
© 2025

Funding

The original feasibility trial was supported by the Villanova University Office of the Provost and Fitzpatrick College of Nursing. The author is currently supported by the National Institute of General Medical Sciences of the National Institutes of Health (award number 5R16GM153679-02). Although the present study was not funded by this award, it is related to the author's broader research program supported by NIGMS. In accordance with NIH Public Access Policy, the author will deposit the final peer reviewed manuscript in PubMed Central. The funders had no role in the design, analysis, or reporting of the current study.

ASJC Scopus Subject Areas

  • Clinical Psychology
  • Psychiatry and Mental health

Keywords

  • Biofeedback
  • Digital health
  • Disordered eating
  • Heart rate variability
  • Interoception
  • Interoceptive sensibility
  • Multidimensional Assessment of Interoceptive Awareness-2

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