Linking Protein Structure and Function to Medical Applications Through 3-D Molecular Modeling

Riti Vohra; Valentina Ramirez; Guy Merus; Emily Schmitt Lavin

Linking Protein Structure and Function to Medical Applications Through 3-D Molecular Modeling

Riti Vohra
, Valentina Ramirez
, Guy Merus
, Emily Schmitt Lavin

Department of Biological Sciences

Research output: Contribution to conference › Presentation

Abstract

Through the use of protein visualization software, such as JMOL, it is possible to design and ultimately print 3-D structural protein models. Literary review and protein database files help shed light on the important structural components of proteins. As an example, the Angiotensin II, AT1 type receptor, known by its protein database file, 4ZUD, was selected to demonstrate this process. We observed its interaction with a well-known anti-hypertensive drug, Benicar™ (olmesartan), to better explain the structure and function of this drug and its receptor. 3-D molecular modeling is a valuable tool for visually understanding and identifying anatomical and physiological relationships.

Original language	American English
State	Published - Oct 22 2016
Event	Human Anatomy & Physiology Society (HAPS) Southern Regional Meeting - Nova Southeastern University, Fort Lauderdale, United States Duration: Oct 22 2016 → Oct 22 2016

Conference

Conference	Human Anatomy & Physiology Society (HAPS) Southern Regional Meeting
Country/Territory	United States
City	Fort Lauderdale
Period	10/22/16 → 10/22/16

Disciplines

Biochemistry, Biophysics, and Structural Biology
Life Sciences

Cite this

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title = "Linking Protein Structure and Function to Medical Applications Through 3-D Molecular Modeling",

abstract = " Through the use of protein visualization software, such as JMOL, it is possible to design and ultimately print 3-D structural protein models. Literary review and protein database files help shed light on the important structural components of proteins. As an example, the Angiotensin II, AT1 type receptor, known by its protein database file, 4ZUD, was selected to demonstrate this process. We observed its interaction with a well-known anti-hypertensive drug, Benicar{\texttrademark} (olmesartan), to better explain the structure and function of this drug and its receptor. 3-D molecular modeling is a valuable tool for visually understanding and identifying anatomical and physiological relationships.",

author = "Riti Vohra and Valentina Ramirez and Guy Merus and \{Schmitt Lavin\}, Emily",

year = "2016",

month = oct,

day = "22",

language = "American English",

note = "Human Anatomy \& Physiology Society (HAPS) Southern Regional Meeting ; Conference date: 22-10-2016 Through 22-10-2016",

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TY - CONF

T1 - Linking Protein Structure and Function to Medical Applications Through 3-D Molecular Modeling

AU - Vohra, Riti

AU - Ramirez, Valentina

AU - Merus, Guy

AU - Schmitt Lavin, Emily

PY - 2016/10/22

Y1 - 2016/10/22

N2 - Through the use of protein visualization software, such as JMOL, it is possible to design and ultimately print 3-D structural protein models. Literary review and protein database files help shed light on the important structural components of proteins. As an example, the Angiotensin II, AT1 type receptor, known by its protein database file, 4ZUD, was selected to demonstrate this process. We observed its interaction with a well-known anti-hypertensive drug, Benicar™ (olmesartan), to better explain the structure and function of this drug and its receptor. 3-D molecular modeling is a valuable tool for visually understanding and identifying anatomical and physiological relationships.

AB - Through the use of protein visualization software, such as JMOL, it is possible to design and ultimately print 3-D structural protein models. Literary review and protein database files help shed light on the important structural components of proteins. As an example, the Angiotensin II, AT1 type receptor, known by its protein database file, 4ZUD, was selected to demonstrate this process. We observed its interaction with a well-known anti-hypertensive drug, Benicar™ (olmesartan), to better explain the structure and function of this drug and its receptor. 3-D molecular modeling is a valuable tool for visually understanding and identifying anatomical and physiological relationships.

UR - https://nsuworks.nova.edu/cnso_bio_facpres/380

M3 - Presentation

T2 - Human Anatomy & Physiology Society (HAPS) Southern Regional Meeting

Y2 - 22 October 2016 through 22 October 2016

ER -

Linking Protein Structure and Function to Medical Applications Through 3-D Molecular Modeling

Abstract

Conference

Disciplines

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