Long-Acting Gel Formulations: Advancing Drug Delivery across Diverse Therapeutic Areas

Research output: Contribution to journalReview articlepeer-review

Abstract

This multifaceted landscape of long-acting gels in diverse medical fields, aims to enhance therapeutic outcomes through localized treatment and controlled drug release. The objective involves advancements spanning cancer treatment, immunotherapy, diabetes management, neuroendocrine disorders, ophthalmic applications, contraception, HIV/AIDS treatment, chronic diseases, wound care, and antimicrobial treatments. It explores the potential of long-acting gels to offer sustained and extended drug release, targeted therapy, and innovative administration routes while addressing limitations such as scalability challenges and regulatory hurdles. Future directions focus on personalized therapies, biodegradability, combination therapies, interdisciplinary innovation, regulatory considerations, and patient-centric development. This comprehensive review highlights the pivotal role of long-acting gels in transforming therapeutic approaches and improving patient outcomes across various medical conditions.
Original languageEnglish
Article number493
JournalPharmaceuticals
Volume17
Issue number4
DOIs
StatePublished - Apr 2024

Bibliographical note

Publisher Copyright:
© 2024 by the authors.

Funding

This review article received no external funding.

ASJC Scopus Subject Areas

  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery

Keywords

  • chronic diseases
  • hydrogel therapies
  • localized treatment
  • long-acting gels
  • prolonged release

Disciplines

  • Medical Molecular Biology
  • Pharmacy and Pharmaceutical Sciences

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