Skip to main navigation Skip to search Skip to main content

Malnutrition in orthopaedic trauma outcomes (MOTO): orthopedic trauma patients can be effectively screened and stratified for risk of malnutrition using prealbumin. A preliminary outcome study

  • Anna Jacques
  • , Timothy Niedzielak
  • , Samuel G. Eaddy
  • , Radleigh Santos
  • , Stacey L. Tannenbaum
  • , Joel Rush
  • , Emily Keener
  • , William Neway
  • , Bradley Roth
  • , Edward Perez
  • , Brian J. Cross

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives:To evaluate prealbumin (PAB) as a prognostic indicator for early detection of malnutrition risk upon admission and its correlation with in-hospital complications and length of stay (LOS) in patients with orthopedic trauma.Methods:Design:Retrospective cohort.Setting:Urban academic Level 1 trauma center.Patients/Participants:One hundred fifty-eight patients aged 18 years or older with acute traumatic fractures indicated for primary surgical fixation between 2019 and 2022 were included. Serum laboratory tests consisting of PAB, C-reactive protein, complete blood counts, and complete metabolic panel were obtained within 24 hours of arrival.Outcome Measures and Comparisons:Primary outcome measures included characterization of patient risk factors for increased intensive care unit LOS, hospital LOS, and in-hospital complications. Secondary outcome measures included characterization of patients who were stratified as "at risk"for malnutrition by PAB < 20 mg/dL and identification of complication predictors.Results:Fifty-one (32%) patients were stratified as "at risk"for malnutrition based on serum PAB < 20 mg/dL drawn within 24 hours of arrival. These patients had longer median hospital LOS (P < 0.001), were more likely to stay in the hospital longer than 7 days (P < 0.009) and >14 days (OR = 3.20, 95% CI 1.17-9.07, P < 0.001), and had twice the amount of postoperative complications during their hospital stay (P = 0.04) than patients with PAB ≥ 20 mg/dL.Conclusions:Patients with orthopaedic trauma can reliably and cost-effectively be screened and stratified for risk of malnutrition using PAB drawn with immediate admission labs.

Original languageEnglish
Article numbere402
JournalOTA International
Volume8
Issue number2
DOIs
StatePublished - May 22 2025

Bibliographical note

Publisher Copyright:
Copyright © 2025 The Authors.

ASJC Scopus Subject Areas

  • Orthopedics and Sports Medicine
  • Surgery

Keywords

  • C-reactive protein
  • biomarkers
  • fracture complications
  • injury severity score
  • malnutrition
  • nutrition
  • orthopaedic trauma
  • prealbumin

Fingerprint

Dive into the research topics of 'Malnutrition in orthopaedic trauma outcomes (MOTO): orthopedic trauma patients can be effectively screened and stratified for risk of malnutrition using prealbumin. A preliminary outcome study'. Together they form a unique fingerprint.

Cite this