Abstract
Objectives:To evaluate prealbumin (PAB) as a prognostic indicator for early detection of malnutrition risk upon admission and its correlation with in-hospital complications and length of stay (LOS) in patients with orthopedic trauma.Methods:Design:Retrospective cohort.Setting:Urban academic Level 1 trauma center.Patients/Participants:One hundred fifty-eight patients aged 18 years or older with acute traumatic fractures indicated for primary surgical fixation between 2019 and 2022 were included. Serum laboratory tests consisting of PAB, C-reactive protein, complete blood counts, and complete metabolic panel were obtained within 24 hours of arrival.Outcome Measures and Comparisons:Primary outcome measures included characterization of patient risk factors for increased intensive care unit LOS, hospital LOS, and in-hospital complications. Secondary outcome measures included characterization of patients who were stratified as "at risk"for malnutrition by PAB < 20 mg/dL and identification of complication predictors.Results:Fifty-one (32%) patients were stratified as "at risk"for malnutrition based on serum PAB < 20 mg/dL drawn within 24 hours of arrival. These patients had longer median hospital LOS (P < 0.001), were more likely to stay in the hospital longer than 7 days (P < 0.009) and >14 days (OR = 3.20, 95% CI 1.17-9.07, P < 0.001), and had twice the amount of postoperative complications during their hospital stay (P = 0.04) than patients with PAB ≥ 20 mg/dL.Conclusions:Patients with orthopaedic trauma can reliably and cost-effectively be screened and stratified for risk of malnutrition using PAB drawn with immediate admission labs.
| Original language | English |
|---|---|
| Article number | e402 |
| Journal | OTA International |
| Volume | 8 |
| Issue number | 2 |
| DOIs | |
| State | Published - May 22 2025 |
Bibliographical note
Publisher Copyright:Copyright © 2025 The Authors.
ASJC Scopus Subject Areas
- Orthopedics and Sports Medicine
- Surgery
Keywords
- C-reactive protein
- biomarkers
- fracture complications
- injury severity score
- malnutrition
- nutrition
- orthopaedic trauma
- prealbumin
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