Abstract
Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality globally. Despite significant advancements in the development of pharmacological therapies, the challenges of targeted drug delivery to the cardiovascular system persist. Innovative drug-delivery systems have been developed to address these challenges and improve therapeutic outcomes in CVDs. This comprehensive review examines various drug delivery strategies and their efficacy in addressing CVDs. Polymeric nanoparticles, liposomes, microparticles, and dendrimers are among the drug-delivery systems investigated in preclinical and clinical studies. Specific strategies for targeted drug delivery, such as magnetic nanoparticles and porous stent surfaces, are also discussed. This review highlights the potential of innovative drug-delivery systems as effective strategies for the treatment of CVDs.
| Original language | English |
|---|---|
| Article number | 1935 |
| Journal | Pharmaceutics |
| Volume | 15 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2023 |
Bibliographical note
Publisher Copyright:© 2023 by the authors.
Funding
This research received no external funding.
ASJC Scopus Subject Areas
- Pharmaceutical Science
Keywords
- cardiovascular diseases (CVDs)
- drug-delivery systems
- innovative diagnosis and therapies
- nanoparticles
- targeted drug delivery
Disciplines
- Pharmacy and Pharmaceutical Sciences