Abstract
We report our clinical and laboratory experience treating a 50-year-old patient who was critically ill with extensively drug-resistant Acinetobacter baumannii necrotizing pneumonia complicated by empyema in Detroit, Michigan. A precision medicine approach using whole-genome sequencing, susceptibility testing, and synergy analysis guided the selection of rational combination antimicrobial therapy.
| Original language | English |
|---|---|
| Article number | ofac092 |
| Pages (from-to) | ofac092 |
| Journal | Open Forum Infectious Diseases |
| Volume | 9 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1 2022 |
| Externally published | Yes |
Bibliographical note
© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.ASJC Scopus Subject Areas
- Oncology
- Infectious Diseases
Keywords
- Acinetobacter baumannii
- antimicrobial resistance
- combination therapy
- pneumonia
- sulbactam-durlobactam
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