Abstract
The polyamines spermidine and spermine are ubiquitous in animal cells and have been shown to bind to cell membranes. At least two types of immune processes, secretion of active substances during inflammation and lymphocyte activation in cellular immunity, involve cell membranes and calcium ions. Although these processes are activated by polyvalent substances, spermidine and spermine appear to inhibit them. This action of polyamines is discussed in the context of regulating both cell membrane fluidity and calcium fluxes.
| Original language | English |
|---|---|
| Pages (from-to) | 703-713 |
| Number of pages | 11 |
| Journal | Life Sciences |
| Volume | 27 |
| Issue number | 9 |
| DOIs | |
| State | Published - 1980 |
| Externally published | Yes |
ASJC Scopus Subject Areas
- General Biochemistry,Genetics and Molecular Biology
- General Pharmacology, Toxicology and Pharmaceutics
Fingerprint
Dive into the research topics of 'Polyamines spermidine and spermine as modulators of calcium-dependent immune processes'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS