Abstract
Purpose. Potential cognitive and demographic correlates of medication nonadherence in older Hispanic adults with type 2 diabetes were investigated. Methods. Forty community-dwelling participants 65 years of age or older were recruited. Executive control function (ECF) was assessed using the executive clock drawing task (CLOX 1) test and the 25-item Executive Interview. Self-reported medication adherence was measured on a visual analog scale (VAS); measures of glycemic control included glycosylated hemoglobin (HbA1c) concentration. The primary objective was to determine if ECF performance correlated with medication adherence or glycemic control. Results. Participants' mean ± S.D. age was 74.95 ± 7.07 years, and 73% (n = 29) were female. Lower VAS scores correlated with worse CLOX 1 performance (r = 0.38, p = 0.02) and worse HbA1c status (r =-0.42, p = 0.007). Linear regression modeling indicated significant associations between VAS scores and both CLOX 1 results (beta coefficient [β] = 0.41, p = 0.01) and educational level (β = 0.345, p = 0.03). Receiver operating characteristic analysis of CLOX 1 scores (scoring range, 0-15; lower scores indicate greater impairment) showed that a highly sensitive cutoff score for predicting adherence of
| Original language | English |
|---|---|
| Pages (from-to) | e194-e201 |
| Journal | American Journal of Health-System Pharmacy |
| Volume | 75 |
| Issue number | 9 |
| DOIs | |
| State | Published - May 1 2018 |
Bibliographical note
Publisher Copyright:Copyright © 2018, American Society of Health-System Pharmacists, Inc. All rights reserved.
Funding
The study was supported by Nova Southeastern University’s Health Profession Division Research Grant. The authors have declared no other potential conflicts of interest.
ASJC Scopus Subject Areas
- Pharmacy
- Pharmacology
- Health Policy
Keywords
- Executive control function
- Hispanics
- Medication adherence
- Type 2 diabetes
Disciplines
- Pharmacy and Pharmaceutical Sciences
- Pharmacology, Toxicology and Environmental Health
- Health Policy