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Preliminary Results from an RCT Examining the Effects of a Health Behavior Intervention as an Adjunct to Standard Trauma Therapy Among Adults with PTSD

  • Jeffrey L. Kibler
  • , Karla Patricia Molina Valenzuela
  • , Shalynn Murphy
  • , Claudia Ocholski
  • , Dania Dabbagh
  • , Valeria Rangel Cunha
  • , Mindy Ma

Research output: Contribution to journal › Article › peer-review

Abstract

Background/Objectives: Individuals with posttraumatic stress disorder (PTSD) tend to show patterns of elevated cardiovascular disease (CVD) risk earlier in life than the general population. The need for effective interventions for CVD risk-reduction in PTSD is increasingly evident. In this paper we present preliminary results from a longitudinal study of a health behavior intervention, as an adjunct to standard trauma therapy in PTSD. The health behavior intervention addresses CVD-related heath behaviors (physical activity, nutrition, sleep, and stress) in a 12-week program delivered individually in 90-min sessions. Behavior change recommendations included: increased aerobic activity; establishing a balanced diet, enhancing consumption of fruits and vegetables and reducing sugars and fat/saturated fat; incorporating strategies to enhance sleep and lower PTSD-related disruptions (e.g., nightmares); and relaxation and cognitive coping skills to reduce general stress. Methods: Participants were randomized to the health behavior intervention plus standard trauma therapy experimental condition or a standard trauma therapy control group. Outcomes were measured at baseline and after the 12-week intervention phase. Sleep efficiency was measured from actigraphy watches. Physical activity was assessed by self-report and blood pressure was measured using an automated device. The preliminary outcomes are for 29 participants to date who have pre-post data. Results: Sleep efficiency was improved in the intervention group compared to controls (p < 0.05). The intervention group also evidenced significant pre-post increases in moderate physical activity compared to the control group (p < 0.05). Changes in vigorous physical activity did not reach statistical significance in this preliminary sample but the pattern of results are similar to those for moderate activity. Trends toward significance were also observed for pre-post changes in systolic (p = 0.06) and diastolic blood pressure (p = 0.07), with small reductions for the intervention group and increases for the control group. Conclusions: These findings provide preliminary information about the effectiveness of the health behavior intervention on multiple parameters for adults with PTSD. The findings suggest that focusing on health behavior change in multidisciplinary treatments for PTSD may enhance outcomes such as sleep and physical activity and potentially result in greater quality of life. However, the small preliminary sample size reported here should be considered when interpreting the outcomes. Further research may also determine how improvements in health parameters impact other indices of long-term cardiovascular health.

Original languageEnglish
Article number871
JournalBrain Sciences
Volume15
Issue number8
DOIs
StatePublished - Aug 2025

Bibliographical note

Publisher Copyright:
© 2025 by the authors.

Funding

This project is funded by an NIH/NHLBI Research Grant #1R15HL165308-01 (PI: Jeffrey Kibler). The effects of a cognitive behavioral healthy lifestyle intervention for cardiovascular risk reduction in posttraumatic stress disorder.

ASJC Scopus Subject Areas

  • General Neuroscience

Keywords

  • health behaviors
  • healthy lifestyle
  • intervention
  • physical activity
  • PTSD
  • sleep

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