Prolonged post-dural puncture headache in a patient with a renal transplant

Data regarding the duration and severity of postdural puncture headache in patients with probable causes for impairment of cerebral autoregulation and altered rate of cerebrospinal fluid formation are rare. We present an interesting case of a patient with long-standing severe hypertension and resultant end-stage renal disease status postrenal transplant who developed a prolonged postdural puncture headache of mild severity. Its presentation and possible pathophysiological mechanisms are discussed.