Sulfur Mustard Exposure Disrupts Transmembrane Water Channel Proteins In Rabbit Corneas in vivo

  • Madeline Bhend
  • , Duraisamy Kempuraj
  • , Ratnakar Tripathi
  • , Nishant R. Sinha
  • , Will Dunscombe
  • , Brenden R. Lankau
  • , Praveen Kumar Balne
  • , Suneel Gupta
  • , Maxwell Jeffrey
  • , Prashant R. Sinha
  • , Rajiv R. Mohan

Research output: Contribution to journalMeeting abstractpeer-review

Abstract

Aquaporins (AQPs), transmembrane water channel proteins, play an important role in corneal homeostasis and hydration maintenance in vivo. We investigated changes in AQPs levels during acute mustard gas keratopathy condition in vivo by measuring transcript levels in normal and damaged rabbit corneas collected 3-, 7- and 14-days post SM exposure.
Original languageEnglish
Pages (from-to)523
JournalInvestigative Ophthalmology & Visual Science
Volume65
Issue number7
StatePublished - Jun 2024

Funding

Grand number: R01EY034319, R01EY030774, U01EY031650, 1I01BX00357, IK6BX005646.

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