Synthesis of the Proposed Penultimate Biosynthetic Triene Intermediate of Monensin A

Dinesh V. Patel; Frank VanMiddlesworth; John Donaubauer; Peter Gannett; Charles J. Sih

doi:10.1021/ja00275a055

Synthesis of the Proposed Penultimate Biosynthetic Triene Intermediate of Monensin A

Dinesh V. Patel
, Frank VanMiddlesworth
, John Donaubauer
, Peter Gannett
, Charles J. Sih

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

A convergent chiral synthesis of the putative biosynthetic triene precursor, 2b, has been accomplished. Our strategy entails the successive assembly of three key chiral synthons, prepared by enzymatic and microbial techniques.

Original language	English
Pages (from-to)	4603-4614
Number of pages	12
Journal	Journal of the American Chemical Society
Volume	108
Issue number	15
DOIs	https://doi.org/10.1021/ja00275a055
State	Published - 1986
Externally published	Yes

ASJC Scopus Subject Areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja00275a055

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title = "Synthesis of the Proposed Penultimate Biosynthetic Triene Intermediate of Monensin A",

abstract = "A convergent chiral synthesis of the putative biosynthetic triene precursor, 2b, has been accomplished. Our strategy entails the successive assembly of three key chiral synthons, prepared by enzymatic and microbial techniques. ",

author = "Patel, \{Dinesh V.\} and Frank VanMiddlesworth and John Donaubauer and Peter Gannett and Sih, \{Charles J.\}",

year = "1986",

doi = "10.1021/ja00275a055",

language = "English",

volume = "108",

pages = "4603--4614",

journal = "Journal of the American Chemical Society",

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publisher = "American Chemical Society",

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T1 - Synthesis of the Proposed Penultimate Biosynthetic Triene Intermediate of Monensin A

AU - Patel, Dinesh V.

AU - VanMiddlesworth, Frank

AU - Donaubauer, John

AU - Gannett, Peter

AU - Sih, Charles J.

PY - 1986

Y1 - 1986

N2 - A convergent chiral synthesis of the putative biosynthetic triene precursor, 2b, has been accomplished. Our strategy entails the successive assembly of three key chiral synthons, prepared by enzymatic and microbial techniques.

AB - A convergent chiral synthesis of the putative biosynthetic triene precursor, 2b, has been accomplished. Our strategy entails the successive assembly of three key chiral synthons, prepared by enzymatic and microbial techniques.

UR - https://www.scopus.com/pages/publications/0022499278

UR - https://www.scopus.com/pages/publications/0022499278#tab=citedBy

U2 - 10.1021/ja00275a055

DO - 10.1021/ja00275a055

M3 - Article

AN - SCOPUS:0022499278

SN - 0002-7863

VL - 108

SP - 4603

EP - 4614

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 15

ER -

Synthesis of the Proposed Penultimate Biosynthetic Triene Intermediate of Monensin A

Abstract

ASJC Scopus Subject Areas

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