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The genetic code, hadamard matrices and algebraic biology

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Algebraic theory of coding is one of modern fields of applications of algebra. This theory uses matrix algebra intensively. This paper is devoted to an application of Kronecker's matrix forms of presentations of the genetic code for algebraic analysis of a basic scheme of degeneracy of the genetic code. Similar matrix forms are utilized in the theory of signal processing and encoding. The Kronecker family of the genetic matrices is investigated, which is based on the genetic matrix [C A; U G], where C, A, U, G are the letters of the genetic alphabet. This matrix in the third Kronecker power is the (8*8)-matrix, which contains all 64 genetic triplets in a strict order with a natural binary numeration of the triplets by numbers from 0 to 63. Peculiarities of the basic scheme of degeneracy of the genetic code are reflected in the symmetrical black-and-white mosaic of this genetic (8*8)-matrix. This mosaic matrix is connected algorithmically with Hadamard matrices unexpectedly, which are famous in the theory of signal processing and encoding, spectral analysis, quantum mechanics and quantum computers. Furthermore, many kinds of cyclic permutations of genetic elements lead to reconstruction of initial Hadamard matrices into new Hadamard matrices unexpectedly. This demonstrates that matrix algebra is one of promising instruments and of adequate languages in bioinformatics and algebraic biology.

    Original languageEnglish
    Pages (from-to)159-175
    Number of pages17
    JournalJournal of Biological Systems
    Volume18
    Issue numberSPEC. ISSUE 1
    DOIs
    StatePublished - Oct 2010

    ASJC Scopus Subject Areas

    • Ecology
    • Agricultural and Biological Sciences (miscellaneous)
    • Applied Mathematics

    Keywords

    • algebraic biology
    • degeneracy
    • Genetic code
    • Hadamard matrix
    • permutation

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