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The Global Invertebrate Genomics Alliance (GIGA): Developing Community Resources to Study Diverse Invertebrate Genomes

  • Jose V. Lopez
  • , Heather Bracken-Grissom
  • , Allen G. Collins
  • , Timothy Collins
  • , Keith Crandall
  • , Daniel Distel
  • , Casey Dunn
  • , Gonzalo Giribet
  • , Steven Haddock
  • , Nancy Knowlton
  • , Mark Martindale
  • , Mónica Medina
  • , Charles Messing
  • , Stephen J. O'Brien
  • , Gustav Paulay
  • , Nicolas Putnam
  • , Timothy Ravasi
  • , Greg W. Rouse
  • , Joseph F. Ryan
  • , Anja Schulze
  • Gert Wörheide, Maja Adamska, Xavier Bailly, Jesse Breinholt, William E. Browne, M. Christina Diaz, Nathaniel Evans, Jean François Flot, Nicole Fogarty, Matthew Johnston, Bishoy Kamel

Research output: Contribution to journalArticlepeer-review

Abstract

Over 95% of all metazoan (animal) species comprise the "invertebrates, " but very few genomes from these organisms have been sequenced. We have, therefore, formed a "Global Invertebrate Genomics Alliance" (GIGA). Our intent is to build a collaborative network of diverse scientists to tackle major challenges (e.g., species selection, sample collection and storage, sequence assembly, annotation, analytical tools) associated with genome/transcriptome sequencing across a large taxonomic spectrum. We aim to promote standards that will facilitate comparative approaches to invertebrate genomics and collaborations across the international scientific community. Candidate study taxa include species from Porifera, Ctenophora, Cnidaria, Placozoa, Mollusca, Arthropoda, Echinodermata, Annelida, Bryozoa, and Platyhelminthes, among others. GIGA will target 7000 noninsect/nonnematode species, with an emphasis on marine taxa because of the unrivaled phyletic diversity in the oceans. Priorities for selecting invertebrates for sequencing will include, but are not restricted to, their phylogenetic placement; relevance to organismal, ecological, and conservation research; and their importance to fisheries and human health. We highlight benefits of sequencing both whole genomes (DNA) and transcriptomes and also suggest policies for genomic-level data access and sharing based on transparency and inclusiveness. The GIGA Web site (http://giga.nova.edu) has been launched to facilitate this collaborative venture. © 2013 The American Genetic Association 2013. All rights reserved.
Original languageAmerican English
Pages (from-to)1-18
Number of pages18
JournalJournal of Heredity
Volume105
Issue number1
DOIs
StatePublished - Jan 1 2014

Funding

FundersFunder number
National Science Foundation1146337, 0829791, 1146575, 1045243
National Institute of Mental HealthR01MH097062

    ASJC Scopus Subject Areas

    • Genetics(clinical)
    • Genetics
    • Molecular Biology
    • Biotechnology

    Keywords

    • Biodiversity
    • Comparative genomics
    • Consortium
    • Evolution
    • GIGA
    • Invertebrates
    • Metazoa
    • biodiversity
    • consortium
    • evolution
    • comparative genomics
    • metazoa
    • invertebrates
    • Invertebrates/classification
    • Phylogeny
    • Genomics/methods
    • Biological Evolution
    • Animals
    • Organizations
    • Genome

    Disciplines

    • Genetics and Genomics
    • Life Sciences
    • Marine Biology

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