Vulvodynia Study Endorsing Gabapentin for Pelvic Muscle Pain: An In-depth Look

Sexual pain in women remains a difficult and elusive medical condition to treat. Provoked vulvodynia current recommended therapies include pelvic floor physical therapy and psychological interventions including cognitive behavioral therapy (CBT) and sexual counseling. ¹ Pharmacologic options remain limited to topical lidocaine, hormonal cream (typically estrogen + testosterone), and tricyclic antidepressants and their evidence for use remains mixed at best. Vulvodynia etiology is multifactorial and likely involves central sensitization, muscle and tissue nociception, and mucosal mechanoreceptor dysfunction.