Abstract
Vulvovaginal-gingival lichen planus (VVG-LP) consists of a triad of symptoms: vulval, vaginal and gingival lichen planus lesions. The aim of this study was to analyse the prevalence of lesions in various anatomical locations in patients with VVG-LP. The study included 126 consecutive patients with lichen planus. Sixteen (12.7%) patients fulfilled the criteria of VVG-LP. In 12/16 (75%) patients with VVG-LP scalp lesions were also observed. Stratified epithelium-specific antinuclear antibodies (SES-ANA) and anti-ΔNp.3α antibodies were detected in 10/16 (75%) patients with VVG-LP and in 15/110 (13.6%) patients with other forms of lichen planus (p < 0.05). In conclusion, VVG-LP is frequently associated with lichen planopilaris. The new entity may be termed “vulvovaginal-gingival-pilar lichen planus” and our study indicates that SES-ANA is a marker of this type of lichen planus with extensive, severe and refractory- to-therapy involvement of the mucous membranes, skin and scalp.
| Original language | English |
|---|---|
| Pages (from-to) | 92-96 |
| Number of pages | 5 |
| Journal | Acta Dermato-Venereologica |
| Volume | 96 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2016 |
Bibliographical note
Publisher Copyright:© 2016 The Authors.
ASJC Scopus Subject Areas
- Dermatology
Keywords
- Alopecia
- Chronic ulcerative stomatitis
- Dermoscopy
- Frontal fibrosing alopecia
- Oral lichen planus
- Trichoscopy
- Vulvitis
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