Biological and Human Health Effects of the Chlorinated Dioxin 2,3,7,8 – Tetrachlorodibenzo-P-Dioxin (TCDD)

  • Paul Patterson

    Student thesis: Master's ThesisMaster of Science

    Abstract

    2,3,7,8-Tetrachlorodibenzo-para-dioxin (TCDD) is found as a contaminant of certain herbicides. Vietnam veterans and others exposed to this dioxin have suffered a wide range of serious health problems, many of which appear to be associated with the toxic effects of dioxins demonstrated by experiments in animal systems. The mechanism by which 2,3,7,8-TCDD exerts its toxic effects is most likely based on microsomal enzyme induction, yet the exact workings of the mechanism remain to be discovered. This paper is the result of an extensive survey of the recent scientific literature describing research on the biological effects of dioxins, specifically, 2,3,7,8-TCDD and its possible effects on human health.
    Date of AwardJan 1 1981
    Original languageEnglish
    SupervisorRobert A. Menzies (Supervisor)

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